Good Manufacturing Practice Validation and Radiation Dosimetry for the Clinical Application of a Novel α7-nAChR Radioligand: [<sup>11</sup>C]KIn83

Good Manufacturing Practice Validation and Radiation Dosimetry for the Clinical Application of a Novel α7-nAChR Radioligand: [<sup>11</sup>C]KIn83

Nicotinic acetylcholine receptor (α7-nAChR) plays a crucial role in cognitive functions like memory and attention. Positron emission tomography (PET) imaging of α7-nAChR is gaining attraction for understanding and monitoring central nervous system disorders, such as Alzheimer’s disease, Parkinson’s...

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Bibliographic Details
Main Authors: Zhisheng Jia, Martin Bolin, Anton Forsberg Morén, Prodip Datta, Heba Asem, Hans Ågren, Bengt Långström, Agneta Nordberg, Christer Halldin, Sangram Nag
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Molecules
Subjects:
nicotinic acetylcholine receptor
Alzheimer’s disease
non-human primate
dosimetry
PET
Online Access:https://www.mdpi.com/1420-3049/30/6/1356
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