Unraveling the dual role of METTL3-mediated m6A RNA modification in bladder cancer: mechanisms, therapeutic vulnerabilities, and clinical implications

Bladder cancer (BC) remains challenging due to its recurrence and metastasis, with METTL3-mediated m6 A RNA modification emerging as a key oncogenic driver. This review synthesizes METTL3’s roles in BC progression, including tumor initiation, metastasis, stemness, and therapy resistance. We detail i...

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Bibliographic Details
Main Authors: Hua Chun, Kangzhuo Baima
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Cancer Biology & Therapy
Subjects:
Online Access:https://www.tandfonline.com/doi/10.1080/15384047.2025.2545057
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