Regulatory roles of NAMPT and NAD+ metabolism in uterine leiomyoma progression: Implications for ECM accumulation, stemness, and microenvironment

Regulatory roles of NAMPT and NAD+ metabolism in uterine leiomyoma progression: Implications for ECM accumulation, stemness, and microenvironment

Uterine leiomyoma (UL), commonly referred to as benign tumors, is characterized by excessive cell proliferation, extracellular matrix (ECM) accumulation, and the presence of stem cell-like properties. Nicotinamide adenine dinucleotide (NAD+) metabolism, regulated in part by nicotinamide phosphoribos...

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Bibliographic Details
Main Authors: Yi-Fen Chiang, Ko-Chieh Huang, Tsui-Chin Huang, Hsin-Yuan Chen, Mohamed Ali, Ayman Al-Hendy, Pei-Shen Huang, Shih-Min Hsia
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Redox Biology
Subjects:
Uterine leiomyoma
NAMPT
NAD
Extracellular matrix
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231724003896
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