Single-cell and spatiotemporal transcriptomic profiling of brain immune infiltration following Venezuelan equine encephalitis virus infection

Single-cell and spatiotemporal transcriptomic profiling of brain immune infiltration following Venezuelan equine encephalitis virus infection

Neurotropic alphaviruses such as Venezuelan equine encephalitis virus (VEEV) are critical human pathogens that continually expand to naïve populations and for which there are no licensed vaccines or therapeutics. VEEV is highly infectious via the aerosol route and is a recognized weaponizable biothr...

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Bibliographic Details
Main Authors: Margarita V. Rangel, Aimy Sebastian, Nicole F. Leon, Ashlee M. Phillips, Bria M. Gorman, Nicholas R. Hum, Dina R. Weilhammer
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Immunology
Subjects:
single cell RNA sequencing
Venezuelan equine encephalitis virus (VEEV)
neuroimmunology
encephalitis
spatial trancriptomics
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1497839/full
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https://www.frontiersin.org/articles/10.3389/fimmu.2024.1497839/full

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