A streptococcal lipid toxin induces membrane permeabilization and pyroptosis leading to fetal injury
Abstract Group B streptococci (GBS) are Gram‐positive bacteria that cause infections in utero and in newborns. We recently showed that the GBS pigment is hemolytic and increased pigment production promotes bacterial penetration of human placenta. However, mechanisms utilized by the hemolytic pigment...
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| Main Authors: | Christopher Whidbey, Jay Vornhagen, Claire Gendrin, Erica Boldenow, Jenny Mae Samson, Kenji Doering, Lisa Ngo, Ejiofor A D Ezekwe, Jens H Gundlach, Michal A Elovitz, Denny Liggitt, Joseph A Duncan, Kristina M Adams Waldorf, Lakshmi Rajagopal |
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| Format: | Article |
| Language: | English |
| Published: |
Springer Nature
2015-03-01
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| Series: | EMBO Molecular Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.15252/emmm.201404883 |
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