Preliminary high-dose irradiation of the recipient and associated damage of bone marrow stromal compartment enables bone marrow stroma transplantation

Abstract Transplantability of allogeneic mesenchymal stem cells (MSCs) as a stable engraftment and participation in physiological renewal of bone marrow (BM) stroma remains an open question. We hypothesized that a necessary condition for successful MSCs transplantation is the prior significant damag...

Full description

Saved in:
Bibliographic Details
Main Authors: Aleksei Bigildeev, Evgeny Bigildeev, Eugenia Bulygina, Svetlana Tsygankova, Mariia Gusakova, Olga Illarionova
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Online Access:https://doi.org/10.1038/s41598-025-07709-9
Tags: Add Tag
No Tags, Be the first to tag this record!