Osteonecrosis of the jaw associated with ustekinumab in the treatment of Crohn's disease

MRONJ is a well-known side effect of antiresorptive and antiangiogenic drug treatment. Crohn's disease involves pro-inflammatory interleukins IL-12 and IL-23. Ustekinumab is a targeted therapy antagonist of the p40 subunit of IL-12 and -23 indicated in the treatment of immune-mediated inflammat...

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Bibliographic Details
Main Authors: Jean Massaad, Michèle Magremanne
Format: Article
Language:English
Published: Elsevier 2024-10-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024145975
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