TRPV1 inhibition sensitizes tumors to PD-1 blockade by reversing resistance to CTL-mediated killing
Abstract Resistance to immune checkpoint blockade (ICB) therapy remains a major obstacle to successful cancer treatment and represents a significant unmet clinical need. Identifying clinically actionable targets to overcome this resistance is therefore essential for developing effective combination...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-07-01
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| Series: | Scientific Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/s41598-025-07120-4 |
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