Prevalence of molecular markers of sulfadoxine-pyrimethamine resistance in Plasmodium falciparum isolates from West Africa during 2012–2022

Abstract Sulfadoxine-pyrimethamine (SP) is a key drug recommended by the World Health Organization for the chemoprevention of malaria. However, the strategy is affected by the parasite resistance to SP. This study evaluated Plasmodium falciparum dihydrofolate reductase (Pfdhfr) and dihydropteroate s...

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Bibliographic Details
Main Authors: Ruimin Zhou, Suhua Li, Penghui Ji, Shucheng Ruan, Ying Liu, Chengyun Yang, Dan Qian, Zhiquan He, Dan Wang, Deling Lu, Hongwei Zhang, Yan Deng
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-75828-w
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