Tumor organoids for primary liver cancers: A systematic review of current applications in diagnostics, disease modeling, and drug screening

Tumor organoids for primary liver cancers: A systematic review of current applications in diagnostics, disease modeling, and drug screening

Background & Aims: Liver cancer-related deaths are projected to exceed one million annually by 2030. Existing therapies have significant limitations, including severe side effects and inconsistent efficacy. Innovative therapeutic approaches to address primary liver cancer (PLC) have led to t...

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Main Authors: Ayesha A. Qureshi, Chase J. Wehrle, Sofia Ferreira-Gonzalez, Chunbao Jiao, Hanna Hong, Neda Dadgar, Jorge Arpi-Palacios, Yee Phoon Phong, Jaekeun Kim, Keyue Sun, Koji Hashimoto, David CH. Kwon, Charles Miller, Nic Leipzig, Wen Wee Ma, Jos Melenhorst, Federico Aucejo, Andrea Schlegel
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:JHEP Reports
Subjects:
organoid
3D cell culture
liver cancer
hepatocellular carcinoma
cholangiocarcinoma
diagnosis
Online Access:http://www.sciencedirect.com/science/article/pii/S258955592400168X
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