The Role of Nuclear Phosphoinositides in the p53-MDM2 Nexus

Recent insights into the p53-MDM2 nexus have advanced deeper understanding of their regulation and potent impact on cancer heterogeneity. The roles of nuclear phosphoinositide (PIP<sub>n</sub>s) in modulating this pathway are emerging as a key mechanism. Here, we dissect the molecular me...

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Bibliographic Details
Main Authors: Jeong Hyo Lee, Muhammad Khalil Salah, Xiangqin Chen, Nickolas Vladimir Kucherenko, Vincent L. Cryns, Richard A. Anderson
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Cells
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Online Access:https://www.mdpi.com/2073-4409/14/15/1126
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