Association of Genetic Polymorphism of ABCG2 Gene and the Occurrence of Oxaliplatin-Induced Peripheral Neuropathy in Patients with Colorectal Cancer

Association of Genetic Polymorphism of ABCG2 Gene and the Occurrence of Oxaliplatin-Induced Peripheral Neuropathy in Patients with Colorectal Cancer

Background: Oxaliplatin use in gastrointestinal malignancies is limited by neurotoxicity. This study aims to identify single-nucleotide polymorphisms (SNPs) in the ABCG2 gene associated with oxaliplatin-induced peripheral neuropathy (OIPN) in Egyptian Colorectal Cancer (CRC) patients treated with ox...

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Bibliographic Details
Main Authors: Inas M. M. Ahmed, Lamia M. El Wakeel, Amr S. Saad, Ahmed A. Emam, Raafat R. Abdel-Malek, Abdel Hady A. Abdel Wahab
Format: Article
Language:English
Published: Ain Shams University 2023-12-01
Series:Archives of Pharmaceutical Sciences Ain Shams University
Subjects:
: oxaliplatin-induced peripheral neuropathy
abcg2 gene
colorectal cancer
high-resolution melting technique
3500 genetic analyzer.
Online Access:https://aps.journals.ekb.eg/article_332148.html
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