Krüppel-like factor 5 remodels lipid metabolism in exercised skeletal muscle

Krüppel-like factor 5 remodels lipid metabolism in exercised skeletal muscle

Regular physical activity induces a variety of health benefits, preventing and counteracting diseases caused by a sedentary lifestyle. However, the molecular underpinnings of skeletal muscle plasticity in exercise remain poorly understood. We identified a role of the Krüppel-Like Factor 5 (Klf5) in...

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Main Authors: Konstantin Schneider-Heieck, Joaquín Pérez-Schindler, Jonas Blatter, Laura M. de Smalen, Wandrille Duchemin, Stefan A. Steurer, Bettina Karrer-Cardel, Danilo Ritz, Christoph Handschin
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Molecular Metabolism
Subjects:
Skeletal muscle
Klf5
Exercise
Lipid metabolism
Stress response
Transcriptional regulation
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877825000614
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