Patterns of the within-host evolution of human norovirus in immunocompromised individuals and implications for treatmentResearch in context

Patterns of the within-host evolution of human norovirus in immunocompromised individuals and implications for treatmentResearch in context

Summary: Background: Currently, there is no licensed treatment for chronic norovirus infections, but the use of intra-duodenally-delivered immunoglobulins is promising; nevertheless, varying results have limited their wide use. Little is known about the relationship between norovirus genetic divers...

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Main Authors: Ray W. Izquierdo-Lara, Nele Villabruna, Dennis A. Hesselink, Claudia M.E. Schapendonk, Sol Ribó Pons, David Nieuwenhuijse, Jenny I.J. Meier, Ian Goodfellow, Virgil A.S.H. Dalm, Pieter L.A. Fraaij, Jeroen J.A. van Kampen, Marion P.G. Koopmans, Miranda de Graaf
Format: Article
Language:English
Published: Elsevier 2024-11-01
Series:EBioMedicine
Subjects:
Norovirus
Chronic infections
Immunocompromised
Virus evolution
Immunoglobulin
Antigenic evolution
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396424004274
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http://www.sciencedirect.com/science/article/pii/S2352396424004274

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