Metformin delays the decline in thermogenic function of brown adipose tissue in a mouse model of Hutchinson-Gilford progeria syndrome
Brown adipose tissue (BAT) is the primary site for non-shivering thermogenesis in the body and plays a crucial role in maintaining core body temperature. However, its function gradually declines with age. To mitigate the age-related decline in BAT thermogenic capacity, we treated progeroid mice with...
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Main Authors: | Xin Xiang, Yuyue Feng, Hongcheng Li, Wenbo Li, Jia Li, Zhu Xia, Hua Pang, Zhengjie Wang |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2025-03-01
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Series: | Experimental Gerontology |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0531556525000300 |
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