Exosome-Derived miRNAs in Liquid Biopsy for Lung Cancer
Exosome-derived microRNAs (miRNAs) are potential biomarkers for lung cancer detection and monitoring through liquid biopsy. These small, non-coding RNA molecules are found within exosomes, which are extracellular vesicles released from cells. Their stability in biofluids, such as blood, positions th...
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| Format: | Article |
| Language: | English |
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MDPI AG
2024-12-01
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| Series: | Life |
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| Online Access: | https://www.mdpi.com/2075-1729/14/12/1608 |
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| author | Israel Martínez-Espinosa José A. Serrato Carlos Cabello-Gutiérrez Ángeles Carlos-Reyes Blanca Ortiz-Quintero |
| author_facet | Israel Martínez-Espinosa José A. Serrato Carlos Cabello-Gutiérrez Ángeles Carlos-Reyes Blanca Ortiz-Quintero |
| author_sort | Israel Martínez-Espinosa |
| collection | DOAJ |
| description | Exosome-derived microRNAs (miRNAs) are potential biomarkers for lung cancer detection and monitoring through liquid biopsy. These small, non-coding RNA molecules are found within exosomes, which are extracellular vesicles released from cells. Their stability in biofluids, such as blood, positions them as candidates for minimally invasive diagnostics. Multiple studies have shown that lung cancer patients exhibit distinct miRNA profiles compared to healthy individuals. This finding suggests that exosome-derived miRNAs could serve as valuable biomarkers for diagnosis, prognosis, and evaluating therapeutic responses. This review summarizes recent research on exosome-derived miRNAs in liquid biopsies, including blood, pleural effusion, and pleural lavage, as biomarkers for lung cancer, focusing on publications from the last five years. |
| format | Article |
| id | doaj-art-55c4c62b3fe34e01b5eeaaf69faed63d |
| institution | Kabale University |
| issn | 2075-1729 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Life |
| spelling | doaj-art-55c4c62b3fe34e01b5eeaaf69faed63d2024-12-27T14:36:05ZengMDPI AGLife2075-17292024-12-011412160810.3390/life14121608Exosome-Derived miRNAs in Liquid Biopsy for Lung CancerIsrael Martínez-Espinosa0José A. Serrato1Carlos Cabello-Gutiérrez2Ángeles Carlos-Reyes3Blanca Ortiz-Quintero4Department of Molecular Biomedicine and Translational Research, Instituto Nacional de Enfermedades Respiratorias Ismael Cosío Villegas, Mexico City 14080, MexicoDepartment of Molecular Biomedicine and Translational Research, Instituto Nacional de Enfermedades Respiratorias Ismael Cosío Villegas, Mexico City 14080, MexicoDepartment of Research in Virology and Mycology, Instituto Nacional de Enfermedades Respiratorias Ismael Cosío Villegas, Mexico City 14080, MexicoLaboratory of Onco-Immunobiology, Instituto Nacional de Enfermedades Respiratorias Ismael Cosío Villegas, Mexico City 14080, MexicoDepartment of Molecular Biomedicine and Translational Research, Instituto Nacional de Enfermedades Respiratorias Ismael Cosío Villegas, Mexico City 14080, MexicoExosome-derived microRNAs (miRNAs) are potential biomarkers for lung cancer detection and monitoring through liquid biopsy. These small, non-coding RNA molecules are found within exosomes, which are extracellular vesicles released from cells. Their stability in biofluids, such as blood, positions them as candidates for minimally invasive diagnostics. Multiple studies have shown that lung cancer patients exhibit distinct miRNA profiles compared to healthy individuals. This finding suggests that exosome-derived miRNAs could serve as valuable biomarkers for diagnosis, prognosis, and evaluating therapeutic responses. This review summarizes recent research on exosome-derived miRNAs in liquid biopsies, including blood, pleural effusion, and pleural lavage, as biomarkers for lung cancer, focusing on publications from the last five years.https://www.mdpi.com/2075-1729/14/12/1608exosome-derived miRNAsliquid biopsylung cancer |
| spellingShingle | Israel Martínez-Espinosa José A. Serrato Carlos Cabello-Gutiérrez Ángeles Carlos-Reyes Blanca Ortiz-Quintero Exosome-Derived miRNAs in Liquid Biopsy for Lung Cancer Life exosome-derived miRNAs liquid biopsy lung cancer |
| title | Exosome-Derived miRNAs in Liquid Biopsy for Lung Cancer |
| title_full | Exosome-Derived miRNAs in Liquid Biopsy for Lung Cancer |
| title_fullStr | Exosome-Derived miRNAs in Liquid Biopsy for Lung Cancer |
| title_full_unstemmed | Exosome-Derived miRNAs in Liquid Biopsy for Lung Cancer |
| title_short | Exosome-Derived miRNAs in Liquid Biopsy for Lung Cancer |
| title_sort | exosome derived mirnas in liquid biopsy for lung cancer |
| topic | exosome-derived miRNAs liquid biopsy lung cancer |
| url | https://www.mdpi.com/2075-1729/14/12/1608 |
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