Preclinical development of an immunoassay for the detection of TREM2: a new biomarker for Alzheimer’s disease

Preclinical development of an immunoassay for the detection of TREM2: a new biomarker for Alzheimer’s disease

Abstract Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by the accumulation of amyloid-β (Aβ) plaques and neurofibrillary tangles composed of hyperphosphorylated tau protein. The combination of biomarkers is crucial for AD diagnosis. The triggering receptor expressed on myelo...

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Bibliographic Details
Main Authors: Jie Hu, Huimei Zeng, Jiaqi Lu, Tianpeng Li, Xue Liu, Yang Liu, Weihuan Wen, Weijun Shen, Hongying Chen, Zhicheng Chen
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Subjects:
Alzheimer’s disease
Biomarker
TREM2
Detection
Online Access:https://doi.org/10.1038/s41598-025-09262-x
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