Machine learning proteochemometric models for Cereblon glue activity predictions

Machine learning proteochemometric models for Cereblon glue activity predictions

Targeted protein degradation (TPD) is a rapidly developing drug discovery technique with unique efficacy and target scope stemming from its degradation-based activity. Molecular glue degraders are a promising arm of TPD, as evidenced by the FDA-approved therapeutics within this class, the increasing...

Full description

Saved in:
Bibliographic Details
Main Authors: Francis J. Prael, III, Jiayi Cox, Noé Sturm, Peter Kutchukian, William C. Forrester, Gregory Michaud, Jutta Blank, Lingling Shen, Raquel Rodríguez-Pérez
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Artificial Intelligence in the Life Sciences
Subjects:
Machine learning
Glues
Targeted protein degradation
Cereblon
Proteochemometric models
Chemogenomics
Online Access:http://www.sciencedirect.com/science/article/pii/S2667318524000072
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

http://www.sciencedirect.com/science/article/pii/S2667318524000072

Similar Items