Evaluating vitamin C-related gene-environment and metabolite-environment interaction effects on intraocular pressure in the Canadian Longitudinal Study on Aging

Evaluating vitamin C-related gene-environment and metabolite-environment interaction effects on intraocular pressure in the Canadian Longitudinal Study on Aging

Abstract High intraocular pressure (IOP) is an important risk factor for glaucoma, which is influenced by genetic and environmental factors. However, the etiology of high IOP remains uncertain. Metabolites are compounds involved in metabolism which provide a link between the internal (genetic) and e...

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Bibliographic Details
Main Authors: Rebecca Lelievre, Mohan Rakesh, Pirro G. Hysi, Julian Little, Ellen E. Freeman, Marie-Hélène Roy-Gagnon
Format: Article
Language:English
Published: BMC 2025-01-01
Series:BMC Genomic Data
Subjects:
CLSA
Gene-environment
Intraocular pressure
Metabolites
Online Access:https://doi.org/10.1186/s12863-025-01301-w
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