Personality and neuropsychiatric symptoms in individuals diagnosed with long COVID
Abstract Objective This study investigates persistent physical and neuropsychiatric symptoms in Long COVID, focusing on their severity and assessing risk/resilience factors, including conscientiousness and neuroticism. The study utilizes a mediation model to explore the potential role of psychologic...
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BMC
2024-12-01
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| Series: | BMC Infectious Diseases |
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| Online Access: | https://doi.org/10.1186/s12879-024-10308-0 |
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| author | Asia Avinir Aviv Kupershmidt Dana Amsterdam Guy Choshen Jacob Nadav Ablin Odelia Elkana |
| author_facet | Asia Avinir Aviv Kupershmidt Dana Amsterdam Guy Choshen Jacob Nadav Ablin Odelia Elkana |
| author_sort | Asia Avinir |
| collection | DOAJ |
| description | Abstract Objective This study investigates persistent physical and neuropsychiatric symptoms in Long COVID, focusing on their severity and assessing risk/resilience factors, including conscientiousness and neuroticism. The study utilizes a mediation model to explore the potential role of psychological distress in mediating its impact on cognitive decline. Methods In an online survey, 114 participants diagnosed with Long COVID completed assessments, including the Patient Health Questionnaire (PHQ-9) and Generalized Anxiety Disorder (GAD-7) for psychological distress, Subjective Cognitive Decline (SCD) questionnaire for cognitive decline, Pittsburgh Sleep Quality Index (PSQI) for sleep disorders, and Multidimensional Scale of Perceived Social Support (MSPSS) with “BIG-5 inventory” subscales for risk/resilience factors. Results Findings showed high rates of depressive disorders (45.6%), generalized anxiety disorders (21%), sleep disturbances (76.3%), and reported cognitive changes (94.7%). Conscientiousness negatively correlated with psychological distress (p < .001, r = − .48) and cognitive decline (p < .001, r = − .36), while neuroticism positively correlated (p < .001, r = .62 and p < .001, r = .41, respectively). Social support negatively correlated with psychological distress (p < .001, r = − .52) and cognitive decline (p < .001, r = − .41). Psychological distress fully mediated personality traits and cognitive decline correlations, with significant full mediation for neuroticism [95% CI = (0.22, 0.48)] and conscientiousness [95% CI = (-0.33, -0.07)], controlling for age, gender, other chronic morbidity and social support. Conclusion The study underscores the significance of incorporating psychological interventions into treatment plans to alleviate distress symptoms associated with cognitive decline in conditions like Long COVID. |
| format | Article |
| id | doaj-art-556c534046c5414eb2e2455f3ccd18e7 |
| institution | Kabale University |
| issn | 1471-2334 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Infectious Diseases |
| spelling | doaj-art-556c534046c5414eb2e2455f3ccd18e72024-12-22T12:17:30ZengBMCBMC Infectious Diseases1471-23342024-12-0124111310.1186/s12879-024-10308-0Personality and neuropsychiatric symptoms in individuals diagnosed with long COVIDAsia Avinir0Aviv Kupershmidt1Dana Amsterdam2Guy Choshen3Jacob Nadav Ablin4Odelia Elkana5Behavioral Sciences, The Academic College of Tel-Aviv YaffoDepartment of Internal Medicine H, Tel Aviv Medical CenterDepartment of Internal Medicine H, Tel Aviv Medical CenterDepartment of Internal Medicine B, Meir Medical CenterDepartment of Internal Medicine H, Tel Aviv Medical CenterBehavioral Sciences, The Academic College of Tel-Aviv YaffoAbstract Objective This study investigates persistent physical and neuropsychiatric symptoms in Long COVID, focusing on their severity and assessing risk/resilience factors, including conscientiousness and neuroticism. The study utilizes a mediation model to explore the potential role of psychological distress in mediating its impact on cognitive decline. Methods In an online survey, 114 participants diagnosed with Long COVID completed assessments, including the Patient Health Questionnaire (PHQ-9) and Generalized Anxiety Disorder (GAD-7) for psychological distress, Subjective Cognitive Decline (SCD) questionnaire for cognitive decline, Pittsburgh Sleep Quality Index (PSQI) for sleep disorders, and Multidimensional Scale of Perceived Social Support (MSPSS) with “BIG-5 inventory” subscales for risk/resilience factors. Results Findings showed high rates of depressive disorders (45.6%), generalized anxiety disorders (21%), sleep disturbances (76.3%), and reported cognitive changes (94.7%). Conscientiousness negatively correlated with psychological distress (p < .001, r = − .48) and cognitive decline (p < .001, r = − .36), while neuroticism positively correlated (p < .001, r = .62 and p < .001, r = .41, respectively). Social support negatively correlated with psychological distress (p < .001, r = − .52) and cognitive decline (p < .001, r = − .41). Psychological distress fully mediated personality traits and cognitive decline correlations, with significant full mediation for neuroticism [95% CI = (0.22, 0.48)] and conscientiousness [95% CI = (-0.33, -0.07)], controlling for age, gender, other chronic morbidity and social support. Conclusion The study underscores the significance of incorporating psychological interventions into treatment plans to alleviate distress symptoms associated with cognitive decline in conditions like Long COVID.https://doi.org/10.1186/s12879-024-10308-0Long covidPersonality traitsConscientiousnessNeuroticismPsychological distress, subjective cognitive decline (SCD) |
| spellingShingle | Asia Avinir Aviv Kupershmidt Dana Amsterdam Guy Choshen Jacob Nadav Ablin Odelia Elkana Personality and neuropsychiatric symptoms in individuals diagnosed with long COVID BMC Infectious Diseases Long covid Personality traits Conscientiousness Neuroticism Psychological distress, subjective cognitive decline (SCD) |
| title | Personality and neuropsychiatric symptoms in individuals diagnosed with long COVID |
| title_full | Personality and neuropsychiatric symptoms in individuals diagnosed with long COVID |
| title_fullStr | Personality and neuropsychiatric symptoms in individuals diagnosed with long COVID |
| title_full_unstemmed | Personality and neuropsychiatric symptoms in individuals diagnosed with long COVID |
| title_short | Personality and neuropsychiatric symptoms in individuals diagnosed with long COVID |
| title_sort | personality and neuropsychiatric symptoms in individuals diagnosed with long covid |
| topic | Long covid Personality traits Conscientiousness Neuroticism Psychological distress, subjective cognitive decline (SCD) |
| url | https://doi.org/10.1186/s12879-024-10308-0 |
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