Metabolic balance in colorectal cancer is maintained by optimal Wnt signaling levels

Metabolic balance in colorectal cancer is maintained by optimal Wnt signaling levels

Abstract Wnt pathways are important for the modulation of tissue homeostasis, and their deregulation is linked to cancer development. Canonical Wnt signaling is hyperactivated in many human colorectal cancers due to genetic alterations of the negative Wnt regulator APC. However, the expression level...

Full description

Saved in:
Bibliographic Details
Main Authors: Katharina Imkeller, Giulia Ambrosi, Nancy Klemm, Ainara Claveras Cabezudo, Luisa Henkel, Wolfgang Huber, Michael Boutros
Format: Article
Language:English
Published: Springer Nature 2022-07-01
Series:Molecular Systems Biology
Subjects:
APC
functional genomics
multi‐omic data integration
quantitative signaling
synthetic lethality
Online Access:https://doi.org/10.15252/msb.202110874
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.15252/msb.202110874

Similar Items