Fluorinated Porcine Bone-Derived Hydroxyapatite Promotes Vascularized Osteogenesis by Coordinating Human Bone Marrow Mesenchymal Stem Cell/Human Umbilical Vein Endothelial Cell Complexes

Fluorinated Porcine Bone-Derived Hydroxyapatite Promotes Vascularized Osteogenesis by Coordinating Human Bone Marrow Mesenchymal Stem Cell/Human Umbilical Vein Endothelial Cell Complexes

Biogenic hydroxyapatite is known for its osteoinductive potential due to its similarity to human bone and biocompatibility, but insufficient vascularization compared to autogenous bone during early implantation limits bone integration and osteogenesis. Fluorine has been shown to improve hydroxyapati...

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Bibliographic Details
Main Authors: Xiayi Wu, Chunxin Xu, Junming Feng, Shiyu Wu, Runheng Liu, Wei Qiao, Xin Luo, Shoucheng Chen, Zhipeng Li, Zhuofan Chen
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Bioengineering
Subjects:
angiogenesis
biological hydroxyapatite
fluoride
Online Access:https://www.mdpi.com/2306-5354/11/12/1287
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