Mechanistic Elucidation of green seaweed compounds in orthodontic relapse management via RANKL/TNF-α-mediated ROS/Keap1/Nrf2 signaling: In silico and Ex Vivo studies

Mechanistic Elucidation of green seaweed compounds in orthodontic relapse management via RANKL/TNF-α-mediated ROS/Keap1/Nrf2 signaling: In silico and Ex Vivo studies

Orthodontic relapse, the return to a pre-treatment position after orthodontic correction, is driven by the RANKL/TNF-α-mediated ROS/Keap1/Nrf2 signaling axis. This mechanism triggers aseptic inflammation and oxidative stress, influencing bone resorption and formation. Antioxidants can mitigate oxida...

Full description

Saved in:
Bibliographic Details
Main Authors: Ananto Ali Alhasyimi, Alexander Patera Nugraha, Aulia Ayub, Trianna Wahyu Utami, Timothy Sahala Gerardo, Nuril Farid Abshori, Mohammad Adib Khumaidi, Trina Ekawati Tallei, Nurpudji Astuti Taslim, Bonglee Kim, Raymond Rubianto Tjandrawinata, Apollinaire Tsopmo, Fahrul Nurkolis
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Journal of Agriculture and Food Research
Subjects:
Orthodontic relapse
Green seaweed
Antioxidants
RANKL
ROS/Keap1/Nrf2
Online Access:http://www.sciencedirect.com/science/article/pii/S2666154324004332
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

http://www.sciencedirect.com/science/article/pii/S2666154324004332

Similar Items