Exploring the mediating role of blood metabolites in the relationship between gut microbiota and gastric cancer risk: a Mendelian randomization study

Exploring the mediating role of blood metabolites in the relationship between gut microbiota and gastric cancer risk: a Mendelian randomization study

BackgroundPrior studies have established correlations between gut microbiota (GM) dysbiosis, circulating metabolite alterations, and gastric cancer (GC) risk. However, the causal nature of these associations remains uncertain.MethodsWe utilized summary data from genome-wide association studies (GWAS...

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Bibliographic Details
Main Authors: Xiaocheng Li, Huapeng Lin, Jing Peng, Jianping Gong
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
gut microbiota
metabolites
gastric cancer
Mendelian randomization
causal association
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2024.1453286/full
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