Dexamethasone promotes mesenchymal stem cell apoptosis and inhibits osteogenesis by disrupting mitochondrial dynamics

Dexamethasone promotes mesenchymal stem cell apoptosis and inhibits osteogenesis by disrupting mitochondrial dynamics

Long‐term or heavy use of glucocorticoids can cause severe necrosis of the femoral head, but the underlying mechanisms are still unclear. Recent studies have found that mitochondrial dynamics play an important role in femoral head necrosis. Here, we investigated the effect of dexamethasone on the mi...

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Bibliographic Details
Main Authors: Liang Ma, Xiaobo Feng, Kun Wang, Yu Song, Rongjin Luo, Cao Yang
Format: Article
Language:English
Published: Wiley 2020-02-01
Series:FEBS Open Bio
Subjects:
apoptosis
dexamethasone
mesenchymal stem cells
mitochondria
osteogenesis
salvianolic acid B
Online Access:https://doi.org/10.1002/2211-5463.12771
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https://doi.org/10.1002/2211-5463.12771

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