Lignin Isolated by Microwave-Assisted Acid-Catalyzed Solvolysis Induced Cell Death in Mammalian Tumor Cells by Modulating Apoptotic Pathways

Lignin Isolated by Microwave-Assisted Acid-Catalyzed Solvolysis Induced Cell Death in Mammalian Tumor Cells by Modulating Apoptotic Pathways

Lignin, the most abundant renewable aromatic polymer, has been shown to suppress the growth of mammalian tumor cells. Despite extensive studies on lignin structure and its engineering, there is little information on the biological activity of lignin in relation to its molecular structure or the mole...

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Bibliographic Details
Main Authors: Rio Kashimoto, Eriko Ohgitani, Yutaka Makimura, Tatsuya Miyazaki, Chihiro Kimura, Masaharu Shin-Ya, Hiroshi Nishimura, Giuseppe Pezzotti, Takashi Watanabe, Osam Mazda
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Molecules
Subjects:
lignin
apoptosis
cancer therapy
biomass conversion
TNF-α
NF-κB p65
Online Access:https://www.mdpi.com/1420-3049/29/23/5490
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