ATG3 is subjected to redox regulation to quarantee ATG8 lipidation under ROS-generating stresses

The conjugation of ATG8 (autophagy-related 8) proteins to the lipid phosphatidylethanolamine (PE) is the result of the coordinated and highly regulated action of several ATG core proteins, including ATG4 proteases and the E1 (ATG7)- and E2 (ATG3)- activating enzymes. Although it has been stablished...

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Bibliographic Details
Main Authors: Manuel J. Mallén-Ponce, María Esther Pérez-Pérez
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Autophagy Reports
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Online Access:https://www.tandfonline.com/doi/10.1080/27694127.2023.2300622
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