Hydrogel microsphere stem cell encapsulation enhances cardiomyocyte differentiation and functionality in scalable suspension system

Hydrogel microsphere stem cell encapsulation enhances cardiomyocyte differentiation and functionality in scalable suspension system

A reliable suspension-based platform for scaling engineered cardiac tissue (ECT) production from human induced pluripotent stem cells (hiPSCs) is crucial for regenerative therapies. Here, we compared the production and functionality of ECTs formed using our scaffold-based, engineered tissue microsph...

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Bibliographic Details
Main Authors: Mohammadjafar Hashemi, Ferdous B. Finklea, Hanna Hammons, Yuan Tian, Nathan Young, Emma Kim, Caroline Halloin, Wiebke Triebert, Robert Zweigerdt, Amit Kumar Mitra, Elizabeth A. Lipke
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2025-01-01
Series:Bioactive Materials
Subjects:
Human induced pluripotent stem cells
Suspension culture
Scale-up
Chemically defined media
Aggregate formation
PEG-fibrinogen
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X24003815
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http://www.sciencedirect.com/science/article/pii/S2452199X24003815

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