Evaluation of mathematical models for predicting medicine distribution into breastmilk - considering biological heterogeneity

IntroductionA significant proportion of mothers take medication during the breastfeeding period, however knowledge of infant safety during continued breastfeeding is often limited. Breastmilk exhibits significant physiological heterogeneity, with a range of milk fat (creamatocrit), protein and pH va...

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Bibliographic Details
Main Authors: Sumin Heo, Andrew S. Butler, Marina Stamouli Simoncioni, Sam Moult, Maria Malamatari, Essam Kerwash, Susan Cole
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-11-01
Series:Frontiers in Pharmacology
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Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2024.1507551/full
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