Association of hypertension and plant-based dietary patterns on cognitive impairment: a nationwide cohort study in China
This study investigated the association of hypertension with cognitive impairment and determined whether better adherence to plant-based diet (PBD) patterns may modify the association. We analyzed 4485 elderly individuals with normal cognition at baseline from the Chinese Longitudinal Healthy Longev...
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| Format: | Article |
| Language: | English |
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Tsinghua University Press
2024-11-01
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| Series: | Food Science and Human Wellness |
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| Online Access: | https://www.sciopen.com/article/10.26599/FSHW.2023.9250037 |
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| author | Fang Liang Jialin Fu Gabrielle Turner-McGrievy Yechuang Wang Kai Ding Jing Zeng Justin B Moore Rui Li |
| author_facet | Fang Liang Jialin Fu Gabrielle Turner-McGrievy Yechuang Wang Kai Ding Jing Zeng Justin B Moore Rui Li |
| author_sort | Fang Liang |
| collection | DOAJ |
| description | This study investigated the association of hypertension with cognitive impairment and determined whether better adherence to plant-based diet (PBD) patterns may modify the association. We analyzed 4485 elderly individuals with normal cognition at baseline from the Chinese Longitudinal Healthy Longevity Survey (2011−2018). Cognitive function was assessed by the Mini-mental State Examination (MMSE), and cognitive impairment was defined as an MMSE score below 18 points. Diet patterns were assessed using the overall plant-based diet index (PDI), healthful plant-based diet index (hPDI), and unhealthful plant-based diet index (uPDI) derived from a simplified food frequency questionnaire (FFQ). Blood pressure was measured through physical examination. Cox proportional hazard regression and restricted cubic spline were performed. Participants with hypertension had an increased risk of cognitive impairment compared with normal group. The associations between hypertension and cognitive impairment were more pronounced among participants with lower PDI than those with higher PDI, among participants with lower hPDI than those with higher hPDI, and among participants with higher uPDI than those with lower uPDI. A healthful PBD pattern may attenuate hypertension-induced cognitive impairment, while an unhealthful PBD pattern may exacerbate hypertensioninduced cognitive impairment in elderly. Adherence to healthful PBD pattern could be used to prevent or mitigate adverse neurological effects in the hypertensive population. |
| format | Article |
| id | doaj-art-52b94b0444544d36829207a3fcc274f3 |
| institution | Kabale University |
| issn | 2097-0765 2213-4530 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | Tsinghua University Press |
| record_format | Article |
| series | Food Science and Human Wellness |
| spelling | doaj-art-52b94b0444544d36829207a3fcc274f32025-01-10T06:57:02ZengTsinghua University PressFood Science and Human Wellness2097-07652213-45302024-11-011363544355210.26599/FSHW.2023.9250037Association of hypertension and plant-based dietary patterns on cognitive impairment: a nationwide cohort study in ChinaFang Liang0Jialin Fu1Gabrielle Turner-McGrievy2Yechuang Wang3Kai Ding4Jing Zeng5Justin B Moore6Rui Li7School of Public Health, Wuhan University, Wuhan 430071, ChinaSchool of Public Health, Wuhan University, Wuhan 430071, ChinaDepartment of Health Promotion, Education, and Behavior Arnold School of Public Health, University of South Carolina, Columbia 29208, USASchool of Public Health, Wuhan University, Wuhan 430071, ChinaSchool of Public Health, Wuhan University, Wuhan 430071, ChinaSchool of Public Health, Wuhan University, Wuhan 430071, ChinaDepartment of Implementation Science, Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem 27101, USASchool of Public Health, Wuhan University, Wuhan 430071, ChinaThis study investigated the association of hypertension with cognitive impairment and determined whether better adherence to plant-based diet (PBD) patterns may modify the association. We analyzed 4485 elderly individuals with normal cognition at baseline from the Chinese Longitudinal Healthy Longevity Survey (2011−2018). Cognitive function was assessed by the Mini-mental State Examination (MMSE), and cognitive impairment was defined as an MMSE score below 18 points. Diet patterns were assessed using the overall plant-based diet index (PDI), healthful plant-based diet index (hPDI), and unhealthful plant-based diet index (uPDI) derived from a simplified food frequency questionnaire (FFQ). Blood pressure was measured through physical examination. Cox proportional hazard regression and restricted cubic spline were performed. Participants with hypertension had an increased risk of cognitive impairment compared with normal group. The associations between hypertension and cognitive impairment were more pronounced among participants with lower PDI than those with higher PDI, among participants with lower hPDI than those with higher hPDI, and among participants with higher uPDI than those with lower uPDI. A healthful PBD pattern may attenuate hypertension-induced cognitive impairment, while an unhealthful PBD pattern may exacerbate hypertensioninduced cognitive impairment in elderly. Adherence to healthful PBD pattern could be used to prevent or mitigate adverse neurological effects in the hypertensive population.https://www.sciopen.com/article/10.26599/FSHW.2023.9250037cognitive impairmenthypertensionplant-based dietary patternchinese older adultscohort |
| spellingShingle | Fang Liang Jialin Fu Gabrielle Turner-McGrievy Yechuang Wang Kai Ding Jing Zeng Justin B Moore Rui Li Association of hypertension and plant-based dietary patterns on cognitive impairment: a nationwide cohort study in China Food Science and Human Wellness cognitive impairment hypertension plant-based dietary pattern chinese older adults cohort |
| title | Association of hypertension and plant-based dietary patterns on cognitive impairment: a nationwide cohort study in China |
| title_full | Association of hypertension and plant-based dietary patterns on cognitive impairment: a nationwide cohort study in China |
| title_fullStr | Association of hypertension and plant-based dietary patterns on cognitive impairment: a nationwide cohort study in China |
| title_full_unstemmed | Association of hypertension and plant-based dietary patterns on cognitive impairment: a nationwide cohort study in China |
| title_short | Association of hypertension and plant-based dietary patterns on cognitive impairment: a nationwide cohort study in China |
| title_sort | association of hypertension and plant based dietary patterns on cognitive impairment a nationwide cohort study in china |
| topic | cognitive impairment hypertension plant-based dietary pattern chinese older adults cohort |
| url | https://www.sciopen.com/article/10.26599/FSHW.2023.9250037 |
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