Serum DNA methylome of the colorectal cancer serrated pathway enables non‐invasive detection

Serum DNA methylome of the colorectal cancer serrated pathway enables non‐invasive detection

The clinical relevance of the colorectal cancer serrated pathway is evident, but the screening of serrated lesions remains challenging. We aimed to characterize the serum methylome of the serrated pathway and to evaluate circulating cell‐free DNA (cfDNA) methylomes as a potential source of biomarker...

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Main Authors: María Gallardo‐Gómez, Lara Costas‐Ríos, Carlos A. Garcia‐Prieto, Lara Álvarez‐Rodríguez, Luis Bujanda, Maialen Barrero, Antoni Castells, Francesc Balaguer, Rodrigo Jover, Manel Esteller, Antoni Tardío Baiges, Joaquín González‐Carreró Fojón, Joaquín Cubiella, Loretta De Chiara
Format: Article
Language:English
Published: Wiley 2024-11-01
Series:Molecular Oncology
Subjects:
circulating cell‐free DNA
DNA methylation
non‐invasive biomarkers
screening
serrated colorectal cancer
serrated lesions
Online Access:https://doi.org/10.1002/1878-0261.13573
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https://doi.org/10.1002/1878-0261.13573

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