Furosemide and Serum Protein-Bound Uremic Toxin Concentrations in Patients With CKD

Furosemide and Serum Protein-Bound Uremic Toxin Concentrations in Patients With CKD

Introduction: Furosemide is commonly prescribed to patients with chronic kidney disease (CKD) but may impair the kidney’s excretion of protein-bound uremic toxins (PBUTs) via the organic anion transporters 1 and 3 (OAT1 and OAT3). We evaluated the association between furosemide prescription (status...

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Main Authors: Margaux Costes-Albrespic, Natalia Alencar de Pinho, Islam Amine Larabi, Carolla El Chamieh, Solène M. Laville, Denis Fouque, Maurice Laville, Luc Frimat, Jean-Claude Alvarez, Ziad A. Massy, Sophie Liabeuf, Natalia Alencar De Pinho, Dorothée Cannet, Christian Combe, Aghilès Hamroun, Yves-Edouard Herpe, Christian Jacquelinet, Pascal Morel, Christophe Pascal, Roberto Pecoits-Filho, Joost Schanstra, Bénédicte Stengel, Céline Lange, Oriane Lambert, Marie Metzger
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:Kidney International Reports
Subjects:
CKD
furosemide
loop diuretic
OAT inhibitor
organic anion transporter
uremic toxin
Online Access:http://www.sciencedirect.com/science/article/pii/S2468024925002657
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