New insights into the role of the CHI3L2 protein in invasive ductal breast carcinoma

New insights into the role of the CHI3L2 protein in invasive ductal breast carcinoma

Abstract Chitinase-like proteins have multiple biological functions that promote tumor growth, angiogenesis and metastasis. Expression of CHI3L2, which is similar in structure to CHI3L1, is detected in glioma cells and tumor-associated macrophages (TAMs) in glioma and breast cancer. However, its exa...

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Main Authors: Agnieszka Rusak, Ewa Kątnik, Tomasz Górnicki, Christina Schmuttermaier, Krzysztof Kujawa, Aleksandra Piotrowska, Katarzyna Ratajczak-Wielgomas, Alicja Kmiecik, Andrzej Wojnar, Piotr Dzięgiel, Julia Kzhyshkowska
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Scientific Reports
Subjects:
Chitinase-like proteins
CHI3L2
CHI3L1
Invasive ductal breast carcinoma
ERK1/2
STAT-3
Online Access:https://doi.org/10.1038/s41598-024-77930-5
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https://doi.org/10.1038/s41598-024-77930-5

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