The metabolic profiling of Chinese yam fermented by Saccharomyces boulardii and the biological activities of its ethanol extract in vitro
Chinese yam (Dioscorea opposita Thunb.), as one of the medicinal and edible homologous plants, is rich in various nutrients and functional factors. In this study, Chinese yam fermented by Saccharomyces boulardii was performed to investigate its bioactive components and metabolic profile. And then, t...
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| Format: | Article |
| Language: | English |
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Tsinghua University Press
2024-09-01
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| Series: | Food Science and Human Wellness |
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| Online Access: | https://www.sciopen.com/article/10.26599/FSHW.2022.9250219 |
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| author | Xue Li Yiwen Shao Limin Hao Qiaozhen Kang Xiaolong Wang Jiaqing Zhu Changcheng Zhao Yanling Shi Jike Lu Juanjuan Yi |
| author_facet | Xue Li Yiwen Shao Limin Hao Qiaozhen Kang Xiaolong Wang Jiaqing Zhu Changcheng Zhao Yanling Shi Jike Lu Juanjuan Yi |
| author_sort | Xue Li |
| collection | DOAJ |
| description | Chinese yam (Dioscorea opposita Thunb.), as one of the medicinal and edible homologous plants, is rich in various nutrients and functional factors. In this study, Chinese yam fermented by Saccharomyces boulardii was performed to investigate its bioactive components and metabolic profile. And then, the main bioactive components and biological activities of fermented Chinese yam ethanol extract (FCYE) were evaluated. Results showed that there were 49 up-regulated metabolites and 52 down-regulated metabolites in fermented Chinese yam compared to unfermented Chinese yam. Besides, corresponding metabolic pathways analysis initially revealed that the distribution of bioactive substances was concentrated on alcohol-soluble small molecular substances. Ulteriorly, the total polyphenol content and the total flavonoid content in FCYE were significantly increased, and the corresponding antioxidant and immunomodulatory activities in vitro were also significantly enhanced. Our study provided a new reference for the comprehensive utilization of Chinese yam and laid a theoretical foundation for the development and application of natural probiotic-fermented products. |
| format | Article |
| id | doaj-art-525b5f4b52e04d41b5dde0ae6f49b13c |
| institution | Kabale University |
| issn | 2097-0765 2213-4530 |
| language | English |
| publishDate | 2024-09-01 |
| publisher | Tsinghua University Press |
| record_format | Article |
| series | Food Science and Human Wellness |
| spelling | doaj-art-525b5f4b52e04d41b5dde0ae6f49b13c2025-01-10T06:56:56ZengTsinghua University PressFood Science and Human Wellness2097-07652213-45302024-09-011352718272610.26599/FSHW.2022.9250219The metabolic profiling of Chinese yam fermented by Saccharomyces boulardii and the biological activities of its ethanol extract in vitroXue Li0Yiwen Shao1Limin Hao2Qiaozhen Kang3Xiaolong Wang4Jiaqing Zhu5Changcheng Zhao6Yanling Shi7Jike Lu8Juanjuan Yi9School of Life Sciences, Zhengzhou University, Zhengzhou 450001, ChinaSchool of Life Sciences, Zhengzhou University, Zhengzhou 450001, ChinaSystems Engineering Institute, Academy of Military Sciences (AMS), Beijing 100010, ChinaSchool of Life Sciences, Zhengzhou University, Zhengzhou 450001, ChinaHenan Yinfeng Biological Engineering Technology Co., Ltd., Zhengzhou 450000, ChinaSchool of Life Sciences, Zhengzhou University, Zhengzhou 450001, ChinaSchool of Life Sciences, Zhengzhou University, Zhengzhou 450001, ChinaSchool of Life Sciences, Zhengzhou University, Zhengzhou 450001, ChinaSchool of Life Sciences, Zhengzhou University, Zhengzhou 450001, ChinaSchool of Life Sciences, Zhengzhou University, Zhengzhou 450001, ChinaChinese yam (Dioscorea opposita Thunb.), as one of the medicinal and edible homologous plants, is rich in various nutrients and functional factors. In this study, Chinese yam fermented by Saccharomyces boulardii was performed to investigate its bioactive components and metabolic profile. And then, the main bioactive components and biological activities of fermented Chinese yam ethanol extract (FCYE) were evaluated. Results showed that there were 49 up-regulated metabolites and 52 down-regulated metabolites in fermented Chinese yam compared to unfermented Chinese yam. Besides, corresponding metabolic pathways analysis initially revealed that the distribution of bioactive substances was concentrated on alcohol-soluble small molecular substances. Ulteriorly, the total polyphenol content and the total flavonoid content in FCYE were significantly increased, and the corresponding antioxidant and immunomodulatory activities in vitro were also significantly enhanced. Our study provided a new reference for the comprehensive utilization of Chinese yam and laid a theoretical foundation for the development and application of natural probiotic-fermented products.https://www.sciopen.com/article/10.26599/FSHW.2022.9250219chinese yamsaccharomyces boulardiimetabolitesantioxidantimmunomodulation |
| spellingShingle | Xue Li Yiwen Shao Limin Hao Qiaozhen Kang Xiaolong Wang Jiaqing Zhu Changcheng Zhao Yanling Shi Jike Lu Juanjuan Yi The metabolic profiling of Chinese yam fermented by Saccharomyces boulardii and the biological activities of its ethanol extract in vitro Food Science and Human Wellness chinese yam saccharomyces boulardii metabolites antioxidant immunomodulation |
| title | The metabolic profiling of Chinese yam fermented by Saccharomyces boulardii and the biological activities of its ethanol extract in vitro |
| title_full | The metabolic profiling of Chinese yam fermented by Saccharomyces boulardii and the biological activities of its ethanol extract in vitro |
| title_fullStr | The metabolic profiling of Chinese yam fermented by Saccharomyces boulardii and the biological activities of its ethanol extract in vitro |
| title_full_unstemmed | The metabolic profiling of Chinese yam fermented by Saccharomyces boulardii and the biological activities of its ethanol extract in vitro |
| title_short | The metabolic profiling of Chinese yam fermented by Saccharomyces boulardii and the biological activities of its ethanol extract in vitro |
| title_sort | metabolic profiling of chinese yam fermented by saccharomyces boulardii and the biological activities of its ethanol extract in vitro |
| topic | chinese yam saccharomyces boulardii metabolites antioxidant immunomodulation |
| url | https://www.sciopen.com/article/10.26599/FSHW.2022.9250219 |
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