Topical Application of Orabase Bromelain Gel Reduces Inflammatory Process, Bone Loss and Steatosis in Experimental Periodontitis

Topical Application of Orabase Bromelain Gel Reduces Inflammatory Process, Bone Loss and Steatosis in Experimental Periodontitis

Abstract This study aimed to develop a bromelain-based gel and evaluate its effects in a ligature-induced periodontitis model in rats. The bromelain-based gel was formulated in two concentrations (1% and 10%). Ten animals were used per group: Control, Periodontitis, Periodontitis + Neutral Gel, Peri...

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Main Authors: Even Herlany Pereira Alves, Hélio Mateus Silva Nascimento, Luiz Felipe de Carvalho França, Any Carolina Cardoso Guimarães Vasconcelos, Larissa dos Santos Pessoa, Felipe Rodolfo Pereira da Silva, John Arlley Sousa Pinho de Lira, Paulo Roberto Carneiro Gomes, André dos Santos Carvalho, André Luiz dos Reis Barbosa, Daniel Fernando Pereira Vasconcelos
Format: Article
Language:English
Published: Instituto de Tecnologia do Paraná (Tecpar) 2025-02-01
Series:Brazilian Archives of Biology and Technology
Subjects:
Periodontal disease
Bone biology
Periodontal medicine
Inflammation
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132025000100300&lng=en&tlng=en
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