Complexity of immunobiology of tumor necrosis factor and novel anti-TNF therapy
Tumor Necrosis Factor (TNF) was discovered almost 50 years ago as “serum factor” detected in mice following infections or administration of bacterial lipopolysaccharide (LPS), with a remarkable anti-tumor effect. Molecular cloning showed that this activity is mediated by a small protein (17 kDa), wh...
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| Main Author: | |
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| Format: | Article |
| Language: | Russian |
| Published: |
St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists
2023-06-01
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| Series: | Медицинская иммунология |
| Subjects: | |
| Online Access: | https://www.mimmun.ru/mimmun/article/view/2860 |
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