Evaluation of the role of whiB6 and kdpDE in the dominant multidrug-resistant clone Mycobacterium tuberculosis B0/W148

Evaluation of the role of whiB6 and kdpDE in the dominant multidrug-resistant clone Mycobacterium tuberculosis B0/W148

ABSTRACT Multidrug-resistant (MDR) strains of Mycobacterium tuberculosis represent an obstacle to eradicating tuberculosis (TB) due to the low treatment success rate of MDR TB. Among them, the MDR B0/W148 clone has recently evolved from the M. tuberculosis Beijing lineage 2 and is widely disseminate...

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Main Authors: Isabelle Bonnet, Mickael Orgeur, Florence Brossier, Fadel Sayes, Wafa Frigui, Jan Madacki, Hugo Varet, Aurélie Chauffour, Alexandra Aubry, Nicolas Veziris, Wladimir Sougakoff, Roland Brosch, Régis Tournebize
Format: Article
Language:English
Published: American Society for Microbiology 2025-07-01
Series:Microbiology Spectrum
Subjects:
Mycobacterium tuberculosis
multidrug resistant
B0/W148
whiB6
kdpDE
dissemination
Online Access:https://journals.asm.org/doi/10.1128/spectrum.03224-24
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https://journals.asm.org/doi/10.1128/spectrum.03224-24

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