Sevuparin strongly reduces hepcidin expression in cells, mice, and healthy human volunteers

Abstract Hepcidin is an essential regulator of systemic iron availability mediating both iron uptake from the diet and its release from body stores. Abnormally high hepcidin levels resulting from inflammation in chronic diseases cause iron restriction with the onset of anemia. Restoring physiologica...

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Bibliographic Details
Main Authors: Michela Asperti, Andrea Denardo, Magdalena Gryzik, Kristina E. M. Persson, Göran Westerberg, John Öhd, Maura Poli
Format: Article
Language:English
Published: Wiley 2024-12-01
Series:HemaSphere
Online Access:https://doi.org/10.1002/hem3.70035
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