Sevuparin strongly reduces hepcidin expression in cells, mice, and healthy human volunteers
Abstract Hepcidin is an essential regulator of systemic iron availability mediating both iron uptake from the diet and its release from body stores. Abnormally high hepcidin levels resulting from inflammation in chronic diseases cause iron restriction with the onset of anemia. Restoring physiologica...
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Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2024-12-01
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Series: | HemaSphere |
Online Access: | https://doi.org/10.1002/hem3.70035 |
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