Exploring new mechanisms in cancer molecular pathways and pathogenic cell transformation: PIP4K2A as a prognostic marker and therapeutic target in cutaneous malignant melanoma

Exploring new mechanisms in cancer molecular pathways and pathogenic cell transformation: PIP4K2A as a prognostic marker and therapeutic target in cutaneous malignant melanoma

Abstract Background Cutaneous malignant melanoma is a very aggressive and metastatic form of skin cancer, typically linked with poor outcomes. Advances in genomic analysis have underscored the crucial role of T cells in tumor immunity. Immune checkpoint inhibitors have notably transformed melanoma t...

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Bibliographic Details
Main Authors: Wen-fei Luo, Ding-ming Song, Tong Shen, Yi-bo He, Hong-yang Du, Ming-jue Si, Lu-Wei Fang
Format: Article
Language:English
Published: Springer 2024-11-01
Series:Discover Oncology
Subjects:
Skin cutaneous melanoma (SKCM)
ScRNA-seq
Single-cell transcriptome
Machine learning
PIP4K2A
T cell
Online Access:https://doi.org/10.1007/s12672-024-01555-3
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https://doi.org/10.1007/s12672-024-01555-3

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