Augmentation of PRDX1–DOK3 interaction alleviates rheumatoid arthritis progression by suppressing plasma cell differentiation

Augmentation of PRDX1–DOK3 interaction alleviates rheumatoid arthritis progression by suppressing plasma cell differentiation

Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by persistent inflammation and joint damage, accompanied by the accumulation of plasma cells, which contributes to its pathogenesis. Understanding the genetic alterations occurring during plasma cell differentiation in RA can de...

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Bibliographic Details
Main Authors:	Wenzhen Dang, Xiaomin Wang, Huaying Li, Yixuan Xu, Xinyu Li, Siqi Huang, Hongru Tao, Xiao Li, Yulin Yang, Lijiang Xuan, Weilie Xiao, Dean Guo, Hao Zhang, Qiong Wu, Jie Zheng, Xiaoyan Shen, Kaixian Chen, Heng Xu, Yuanyuan Zhang, Cheng Luo
Format:	Article
Language:	English
Published:	Elsevier 2025-08-01
Series:	Acta Pharmaceutica Sinica B
Subjects:	Rheumatoid arthritis Plasma cell PRDX1 DOK3 Degradation Interaction
Online Access:	http://www.sciencedirect.com/science/article/pii/S2211383525004095
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