Formulation of zein nanoparticles for augmenting the anti-inflammatory activity of dexketoprofen

Formulation of zein nanoparticles for augmenting the anti-inflammatory activity of dexketoprofen

IntroductionTopical delivery of anti-inflammatory drugs is an important strategy for enhancing therapeutic efficacy while minimizing systemic side effects. This study focuses on improving the anti-inflammatory activity of Dexketoprofen by developing zein nanoparticles (ZNs) as a novel topical carrie...

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Main Authors: Mahmoud A. El Hassab, Mona H. Ibrahim, Sherif S. Abdel Mageed, Abdulla M. A. Mahmoud, Zainab Sabry Othman Ahmed, Shaimaa Mosallam, Manar Adel Abdelbari, Eman F. Khaleel, Maram A. El Hasab, Asmaa Elsayyad, Shady Allam, Moaz A. Eltabeeb, Ahmed T. Negmeldin, Wagdy M. Eldehna, Rofida Albash
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Pharmacology
Subjects:
dexketoprofen
zein nanoparticles
inflammation
formalin-induced paw edema
topical delivery
docking
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1560585/full
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https://www.frontiersin.org/articles/10.3389/fphar.2025.1560585/full

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