Accurate HER2 determination in breast cancer: a prominent COF-immobilized enzyme-enhanced electrochemical aptasensor employing 4-acetamidophenol as an efficient mediator

Accurate HER2 determination in breast cancer: a prominent COF-immobilized enzyme-enhanced electrochemical aptasensor employing 4-acetamidophenol as an efficient mediator

Abstract An effective strategy for enzyme-enhanced electrochemical detection of human epidermal growth factor receptor 2 (HER2) is proposed for breast cancer diagnosis. This strategy utilizes a three-dimensional mesoporous covalent organic framework (COF), immobilized horseradish peroxidase (HRP), a...

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Bibliographic Details
Main Authors: Yue Zhang, Shuyi Chen, Jie Ma, Xiaobin Zhou, Xinchen Sun, Chenglin Zhou
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Journal of Nanobiotechnology
Subjects:
Covalent organic framework
Immobilized enzyme
Electrochemical aptasensing
4-acetamidophenol
Breast cancer
Online Access:https://doi.org/10.1186/s12951-024-03035-w
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