Transcriptional programs of Pitx2 and Tfap2a/Tfap2b controlling lineage specification of mandibular epithelium during tooth initiation.

How the dorsal-ventral axis of the vertebrate jaw, particularly the position of tooth initiation site, is established remains a critical and unresolved question. Tooth development starts with the formation of the dental lamina, a localized thickened strip within the maxillary and mandibular epitheli...

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Bibliographic Details
Main Authors: Fan Shao, An-Vi Phan, Wenjie Yu, Yuwei Guo, Jamie Thompson, Carter Coppinger, Shankar R Venugopalan, Brad A Amendt, Eric Van Otterloo, Huojun Cao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-07-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1011364
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