Bisphenol A induces cellular senescence in SW1353 chondrocytes via miRNA-449a-mediated downregulation of SIRT1

Bisphenol A (BPA) is reportedly linked to multiple human diseases. Recent studies found that it disturbs cartilage development and homeostasis. However, the exact molecular mechanisms are mostly unknown. This study aimed to elucidate how BPA impacts chondrocyte senescence and the regulatory molecula...

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Bibliographic Details
Main Authors: Yu Gui, Cun Li, Wenrui Wang, Yuxin Hu, Xiaoying Guo
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:Ecotoxicology and Environmental Safety
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Online Access:http://www.sciencedirect.com/science/article/pii/S0147651325012515
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