Divergent brain solute clearance in rat models of cerebral amyloid angiopathy and Alzheimer’s disease

Divergent brain solute clearance in rat models of cerebral amyloid angiopathy and Alzheimer’s disease

Summary: Brain waste clearance from the interstitial fluid environment is challenging to measure, which has contributed to controversy regarding the significance of glymphatic transport impairment for neurodegenerative processes. Dynamic contrast enhanced MRI (DCE-MRI) with cerebrospinal fluid admin...

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Main Authors: Sunil Koundal, Xinan Chen, Zachary Gursky, Hedok Lee, Kaiming Xu, Feng Liang, Zhongcong Xie, Feng Xu, Hung-Mo Lin, William E. Van Nostrand, Xianfeng Gu, Rena Elkin, Allen Tannenbaum, Helene Benveniste
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:iScience
Subjects:
Biological sciences
Neuroscience
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004224026907
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http://www.sciencedirect.com/science/article/pii/S2589004224026907

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