Classifying breast cancer and fibroadenoma tissue biopsies from paraffined stain-free slides by fractal biomarkers in Fourier Ptychographic Microscopy

Classifying breast cancer and fibroadenoma tissue biopsies from paraffined stain-free slides by fractal biomarkers in Fourier Ptychographic Microscopy

Breast cancer is one of the most spread and monitored pathologies in high-income countries. After breast biopsy, histological tissue is stored in paraffin, sectioned and mounted. Conventional inspection of tissue slides under benchtop light microscopes involves paraffin removal and staining, typical...

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Bibliographic Details
Main Authors: Vittorio Bianco, Marika Valentino, Daniele Pirone, Lisa Miccio, Pasquale Memmolo, Valentina Brancato, Luigi Coppola, Giovanni Smaldone, Massimiliano D’Aiuto, Gennaro Mossetti, Marco Salvatore, Pietro Ferraro
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Computational and Structural Biotechnology Journal
Subjects:
Quantitative Phase Imaging
Fourier Ptychographic Microscopy
Stain-free tissue analysis
Computational pathology
Fractal geometry
Machine learning
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037024000722
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