Recurrent SLCO1B1 and SLCO1B3 mutations identified in three patients with Rotor syndrome

BackgroundRotor syndrome is a rare genetic disease inherited in an autosomal digenic recessive manner. It is caused by pathogenic mutations in both SLCO1B1 and SLCO1B3 genes, and characterized by predominantly conjugated hyperbilirubinemia.MethodsThree Chinese patients clinically diagnosed with Roto...

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Bibliographic Details
Main Authors: Chenyu Zhao, Hui Huang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Medicine
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Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2025.1630360/full
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