Toe1 promotes proliferation and differentiation of neural progenitor cells

Toe1 (target of EGR1, member 1) is a 3′- exonuclease in the deadenylase family, essential for the maturation of small nuclear RNAs. Mutations in Toe1 are linked to pontocerebellar hypoplasia 7 (PCH7), a severe neurodegenerative syndrome affecting infants, characterized by progressive neurodegenerati...

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Bibliographic Details
Main Authors: Tingting Deng, Xingxing Wu, Yujie Wang, Xiaoqin Fan, Bing Hu
Format: Article
Language:English
Published: Elsevier 2024-10-01
Series:Heliyon
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024155661
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