Silence of a dependence receptor CSF1R in colorectal cancer cells activates tumor-associated macrophages

Silence of a dependence receptor CSF1R in colorectal cancer cells activates tumor-associated macrophages

Background Colony-stimulating factor 1 receptor (CSF1R), a classic tyrosine kinase receptor, has been identified as a proto-oncogene in multiple cancers. The CSF1/CSF1R axis is essential for the survival and differentiation of M2-phenotype tumor-associated macrophages (M2 TAMs). However, we found he...

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Main Authors: Rui Ma, Ping Yuan, Xiaolin Wang, Yingjie Li, Meijin Huang, Huichuan Yu, Yanxin Luo, Mingxuan Zhu, Liangliang Bai, Xiaoxia Liu, Shaoyong Peng, Yumo Xie, Hong Bai, Jinxin Lin, Linping Wu
Format: Article
Language:English
Published: BMJ Publishing Group 2022-12-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/10/12/e005610.full
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